NFE2L2 and temporal lobe epilepsy: We have found previously that expression of miR-380-3p was altered in lithium–pilocarpine-induced epilepticus models of Sprague–Dawley rat and in models of temporal lobe epilepsy.37 Current study investigating the link between Nrf2 and miR-380-3p found that expression of miR-380-3p was not altered until PQ dose rose to 10 mg/kg (fold difference = 1.95) or MPTP dose to 30 mg/kg (fold difference = 1.79).