MEG3 and osteosarcoma: For example, MEG3 inhibits proliferation and induces apoptosis in cancer cell lines including MG63, OS-732, SaOS, G292, and 143B (osteosarcoma) [79], OVCAR3 and A2780 [26], MDA-MB-231, MCF-10A and MCF7 (breast) [27], HeLa (cervix), C-33A (cervix) [49], A549/DPP (lung) [38], PRC/PRF/5 (liver) [41], U251 (brain) U87MG (brain) [36], HCT116 (colon) and DLD1 (colon) [54] (Table 1).