MGMT and familial pancreatic carcinoma: They found that haplotypes of O6-methylguanine-DNA methyltransferase (MGMT), MSH6, PMS1 Homolog 2 (PMS2), PMS2-like 3 (PMS2L3), and tumour protein 73 (TP73) were significantly associated with an increased pancreatic cancer risk (P = 0.0015).