A previous study has shown that S100A4 was involved in anoikis resistance of gastric cancer and knockdown of S100A4 expression using siRNA leading to a significant increase in anoikis in gastric cancer cells, while S100A4 expression protected gastric cancer cells from anoikis by an increase in the expression of integrin αv and integrin α5 [88]. Here, S100A4 is linked to gastric cancer.