HOTAIR and neoplasm: Results of meta-analysis, on the basis of two studies, revealed that higher levels of HOTAIR expression were not associated with higher degree of differentiation (OR, 2.31; 95% CI: [0.89, 6.02]; p = 0,09) (Figure 2A), whereas a correlation to advanced tumor stages was seen (OR, 3.44; 95% CI: [1.84, 6.43]; p < 0,001) (Figure 2B).