ALDH1A1 and neoplasm: While the majority of studies examining ALDH1 inhibitors such as DSF and/or DEAB alone [68, 70, 81, 82] and in combination with cisplatin [76, 83] have been carried out using in vitro models, the inhibitory effects of these ALDH1 agents on tumour growth in combination with chemotherapeutic agents such as cisplatin are warranted in clinically relevant tumour xenograft models.