In addition, histomorphometric analysis (Figures 3A, 3B) and Wheat germ agglutinin (WGA) staining (Figures 3C, 3D) demonstrated enhanced myocardial hypertrophy in Ang II-mediated hypertensive rats along with obvious increases in heart weight (HW; Figure 3E) and the ratio of HW and body weight (BW) (Figure 3F). Here, AGT is linked to cardiac hypertrophy.