In the recent study, van Roosmalen et al demonstrated that the expression of SRPK1 was correlated with metastasis of breast cancer into the lung and brain tissues [18], and then knockdown of SRPK1 seemed to repress metastasis of breast cancer into lung and brain tissues, indicating that SRPK1 plays an important role in cancer cell migration and invasion. Here, SRPK1 is linked to breast carcinoma.