To examine the impact of somatic cell SR-B1 on melanoma tumor growth, wild-type C57BL/6J mice (Scarb1+/+), or mice either heterozygous (Scarb1+/−) or homozygous (Scarb1−/−) for deletion of Scarb1, were inoculated subcutaneously with B16F10 melanoma cells (105 cells/flank) and tumor growth was monitored over time by caliper measurements. Here, SCARB1 is linked to neoplasm.