Importantly, myeloid ablation of ABCA1 resulted in an almost 11-fold decrease in granulocytic MDSCs, Ly-6G+Ly-6CLo (median= 0.64 and 0.06 × 106 cells/gram tumor tissue in WT and A1−M/−M, respectively, p=0.04, Figure 5B, top plot). This evidence concerns the gene ABCA1 and neoplasm.