CDK1 and colorectal carcinoma: Compared with the corresponding adjacent normal tissues, CDK1 was significantly up-regulated (more than two-fold [i.e., log2 (fold change) > 1]) in 15 CRC cases (34.88%) (Figure 1D); iASPP was significantly up-regulated (more than two-fold [i.e., log2 (fold change) > 1]) in 15 CRC cases (34.88%) (Figure 1E).