PMS2 and intestinal neoplasm: Cross-comparison of these data with previous genome-wide array comparative genomic hybridization (aCGH) studies of dMMR Mlh3−/−;Pms2−/− intestinal tumors vs paired normal mucosa revealed that the observed irradiated MEF CNA chromosome 7 and chromosome 12 hotspots overlapped with previously observed hotspot regions in Mlh3−/−;Pms2−/− intestinal tumors [10].