Although no such a direct correlation between expression pattern in EMT expression and those of CD44 as found in 4 HCC cell lines, which is maybe because other upstream proteins such as Wnt, TGFβ etc are also involved in EMT expression [19], we found that CD44 expressing cells have generallly have high EMT expression which might be related to liver metastasis [20]. The gene discussed is TGFB1; the disease is hepatocellular carcinoma.