The long-term follow-up study of children exposed to radioactive iodine at the Nevada nuclear weapons test site from 1951 to 1962 (carried out from 1985 to 1986; ~35 years after exposure) (mean dose, 120 ± 167 mGy) found an increased risk of autoimmune thyroid disease (diagnosed by positive anti-thyroglobulin or microsomal antibodies) for those in the highest dose exposure group (>400 mGy) [41]. This evidence concerns the gene TG and autoimmune thyroid disease.