Shiroky et al in a cohort study of 119 RA patients, evaluating the association of thyroid dysfunction in RA, did not find any association between thyroid disorders and age, RF, and also ANA.[10] Our results also confirmed that there was no association between presence of thyroid disorders in RA patients and age, and also IgM RF; however, we think that small difference between our results and Shiroky et al's results was caused by methodological or laboratory analysis differences. The gene discussed is CD40LG; the disease is thyroid gland disorder.