PINK1 and Parkinson disease: The highest number of PD cases are sporadic [157,158], and only 10% are of genetic origin [159], mainly linked to mutations in α-synuclein protein [160], a principal component of Lewy body inclusions [161], parkin [159,162], PTEN-induced putative kinase 1 (PINK1), dardarin, and protein deglycase (DJ-1) [163].