Reduced Mfn2 levels are observed in spontaneously hypertensive or atherosclerosis‐prone rat VSMCs (Chen et al.,2004), whereas Mfn2 overexpression decreases VSMC proliferation and sensitizes cells to H2O2‐induced apoptosis (Guo et al.,2005, 2007). The gene discussed is MFN2; the disease is atherosclerosis.