The pathogenesis of liver enzymes derangement in patients of dengue is not clear as ALT is only expressed in liver and AST is also found in the red blood cells, heart, skeletal muscle, brain and kidneys.24, 25 About 55.68% who had “acute hepatitis” were males and 44.32% were females (p-value 0.68). The gene discussed is GPT; the disease is dengue disease.