Therefore, tumors will be induced or the occurrence of tumors will be accelerated once the effect of Ki67 is inhibited.11-13 Studies have pointed out that Ki67 was correlated to many tumors such as breast cancer,14,15 non-small cell lung cancer, non-Hodgkin’s lymphoma, laryngeal squamous cancer, epithelial ovarian cancer, bladder cancer, cervical cancer, anaplastic oligodendroglioma and colon cancer. The gene discussed is MKI67; the disease is colonic neoplasm.