Even following the failure of ADT, WCE treatment in PCa cells still effectively inhibited the expression of AR, HER2, and HER3 at the protein and mRNA levels, which also resulted in a decrease in AKT phosphorylation and promotion of apoptosis (Figure 7E, lane 6 vs. lane 5, and Figure 7F). The gene discussed is ERBB3; the disease is posterior cortical atrophy.