The phytocannabinoid, THC, increased phosphorylation of eIF2α and the expression of the CHOP10 transcriptional product, TRB3, in hepatocellular carcinoma cells (HEPG2), human glioma cells, and RasV12/E1A-transformed mouse embryonic fibroblasts (MEF, Salazar et al., 2009, 2013; Vara et al., 2013). The gene discussed is TRIB3; the disease is glioma.