WIN55212-2 increased the expression of several phosphatases including dual specificity phosphatases 1 and 10 (DUSP1, DUSP10) and protein tyrosine phosphatase, non-receptor type 6 (PTPN6) in LNCaP prostate cancer cells (Sreevalsan et al., 2011). Here, PTPN6 is linked to Familial prostate cancer.