CNR2 and cervical carcinoma: Consistent with these findings, Met-AEA-induced apoptosis was inhibited by the use of ceramide synthase inhibitors and lipid raft disruptors but not by CB1, CB2, or TRPV1 receptor antagonists in human neuroglioma and cervical carcinoma cells (Hinz et al., 2004b; Eichele et al., 2009).