It has been reported that TRPV1 expression increased with increasing tumor grade in prostate cancer biopsies (Czifra et al., 2009), but it was inversely correlated with tumor stage in bladder cancer (Lazzeri et al., 2005) suggesting that the relationship between TRPV1 expression and tumor behavior may be tumor-type specific. The gene discussed is TRPV1; the disease is neoplasm.