Among them, Soluble NSF Attachment Protein Receptor (SNARE) proteins, synapsin III, VMAT-2 and the DAT are altered in the nigrostriatal system of experimental models of PD (Garcia-Reitböck et al., 2010; Bellucci et al., 2011; Lundblad et al., 2012; Zaltieri et al., 2015). The gene discussed is SLC6A3; the disease is Parkinson disease.