MGMT and glioblastoma: To demonstrate the ability of the conjugates to inhibit MGMT, T98G glioblastoma cells were treated with the MGMT inhibitors O6BG and O6BTG and with the glucose conjugates derived from them, O6BG-Glu and O6BTG-Glu, We observed a clear time-dependent inhibition of MGMT for the glucose-conjugated MGMT inhibitors.