A comparison of cyclin D1 interactomes in MCL cells (JeKo1 and Granta) and in MM cells (U266) revealed that cyclin D1 bound to factors involved in DNA repair (such as PCNA and RAD51), the heat shock response (HSPs, DNAJs), transcriptional regulation (HDACs), and to structural proteins. This evidence concerns the gene PCNA and mantle cell lymphoma.