HBV genotype test (done by clinical assay) was available in 8/12 cases and showed that 3 were HBV genotype B vs. 5 genotype C. 4/12 patients died within 4 weeks of presentation, and 8/12 patients who received rescue NA therapy survived at week 4 of follow-up from onset of liver failure, with 5/12 decline in HBV DNA and ALT and improved liver function. This evidence concerns the gene GPT and Hepatic failure.