Inactivation of the region around rs7208736 has been linked to several malignancies, such as lung, breast, liver, colon, kidney, and brain, with the genes HIC1 (Hypermethylated in cancer 1) and OVCA2 (Ovarian cancer-associated gene 2) being potential tumor suppressors [23, 24]. The gene discussed is OVCA2; the disease is ovarian cancer.