SOD1 and malignant glioma: With regards to other antioxidant enzymes, Xiang et al. [150] found that overexpression of Cu/Zn-SOD (SOD1), CAT and GPx1, in contrast to SOD2, did not suppress apoptosis in selenite-treated prostate cancer cell, while Kim et al. [152] reported that overexpression of SOD1 enhanced cell viability in malignant glioma cells exposed to selenite.