On univariable analysis, predictors of liver fibrosis progression among those presenting with mild-moderate fibrosis at baseline (n = 104) were high baseline ALT (p = 0.011), longer estimated duration of HCV infection prior to liver biopsy (p = 0.029), longer estimated duration of infection before treatment initiation (p = 0.008) and mode of acquisition (p = 0.002) [Table 3]. This evidence concerns the gene GPT and infection.