PDK1 and cancer: More specifically, this type of cancer exhibits aberrant levels of fatty acid-binding protein 5 (FABP5) which through retinoic acid (RA) delivery is known to enhance the peroxisome proliferator-activated receptor β/δ (PPARβ/δ) at the transcriptional level and activate the vascular endothelial growth factor-A (VEGF-A) and PDK1.