Apart from the aforementioned PDK1 inhibitors, one more compound has been recently identified, the inositol 1,3,4,5,6-pentakisphosphate (InsP5), termed 2-O-Bn-InsP5 (Figure 4A), which exerts anti-tumour and pro-apoptotic functions, while at the same time renders cancer cells prone to chemotherapeutic drugs such as tamoxifen and curcumin. Here, PDK1 is linked to cancer.