CRP and obesity due to melanocortin 4 receptor deficiency: After adjustments for obesity and CRP (scored according to the 75th percentile corresponding to 0.3 mg/dL), low 25(OH)D (OR(95%CI), 5 (1.4–18) p < 0.05) and elevated OC (6.7 (1.9–23.8) p < 0.01) levels were found to be significant predictors for FRS, while the finding of elevated OC and/or BAP remained independently associated with PROCAM (3.6 (1.2–10.7), p < 0.05).