TNNI3 and acute myocardial infarction: We considered that the possible reason that there were no effective results in RIPC reduction of cTnI is because myocardial injury during elective PCI is relatively minimal compared with that during acute myocardial infarction, which is mainly due to coronary artery side branch loss and distal embolization during balloon inflation or stent implantation [49, 50].