We found that the production of proinflammatory cytokines, TNF-α, IL-6 and MCP-1, were impaired in the DUSP12 overexpressing cells, associated with reduced activations of p38 and JNK, but not ERK activation in response to LPS stimulation, BCG, and Listeria infection (Figures 2–4). The gene discussed is CCL2; the disease is listeriosis.