The results showed that expression level of serum HSP27 mRNA was higher in patients with NSCLC (42.28 ± 14.28, 2−ΔΔCt) than that in benign lung disease patients (23.66 ± 10.93, 2−ΔΔCt) (P < 0.001) (Table 2, Fig. 3A). Here, HSPB1 is linked to non-small cell lung carcinoma.