Three patients had a missense mutations in ATP1A2 (exon 6, c586C > T, p.Arg196Cys in patient 19; Fig. 3A) or SCN1A (exon 26, c.5516 T > G, p.Ile1839Ser in patient 22; exon 11, c.1688T > A, p.Leu563Gln in patient 30; Fig. 3B), which are genes associated with FHM. Here, ATP1A2 is linked to familial hemiplegic migraine.