CXCL10 (IP-10) is a chemo-attractant for CXCR3+ cells including dendritic cells, T lymphocytes, natural killer cells, and other immune cells39, and also secreted in a MyD88-dependent manner during Chlamydial infection, albeit independently of TLR2 and TLR440. Here, MYD88 is linked to chlamydia trachomatis infectious disease.