APOE and Alzheimer disease: The mean resting motor threshold (RMT) to TMS did not different between APOE3 and APOE4 AD groups, but was lower in both APOE3 (p = 0.007) and APOE4 (p = 0.001) AD patients compared to healthy subjects (HS) (APOE4: 35.7% ± 1.43 maximum stimulator output; APOE3: 38.6% ± 1.94 maximum stimulator output; HS: 43.7% ± 1.49 maximum stimulator output).