Concomitant with elevated IFN-γ and TNF-α levels in blood of patients with psoriasis, TNFRI and TNFR-II were 1.2-fold and 21-fold higher in psoriasis compared to controls (p < 0.05 and p < 0.01) (Fig. 3a). This evidence concerns the gene TNFRSF1B and psoriasis.