-Stimulates DC maturation and migration to LNs; Enhances their ability to process and present dead tumor cell antigens [75]-Increased cytotoxicity of NK and CD8+ T cells [75]-Increased survival of memory CD8+ T cells [75]-Increased pro-inflammatory cytokine release by macrophages [75]-Decreased suppressive function of Treg cells [75]. The gene discussed is CD8A; the disease is neoplasm.