In veterinary medicine, one in vitro study has also shown that masitinib, which inhibits c-Kit, PDGFR and fibroblast growth factor receptor (FGFR), has antiproliferative effects, inhibits the drug efflux function of P-gp and increases the sensitivity to doxorubicin in a drug-resistant canine lymphoid tumor cell line [105]. The gene discussed is PGP; the disease is lymphoid neoplasm.