According to the cut-off values determined by ROC analysis, the positive ratio of antibodies anti-GPIX, anti-GPIb, anti-GPIIIa, anti-GPIIb and anti-P-selectin in our study were 31.84, 32.84, 32.84, 30.35 and 40.30%, respectively, in ITP group, 11.11, 3.97, 3.97, 3.17 and 3.97%, respectively, in non-ITPs and 7.25, 3.38, 5.31, 4.83 and 4.35%, respectively in healthy controls. The gene discussed is ITGA2B; the disease is autoimmune thrombocytopenic purpura.