TGFB1 and ocular melanoma: In the current study, DEX (1 mg/kg) treatment reduced the OM-induced activation of TGF-β signaling transduction pathways, observed by the reduction of immunoexpression of TGF-β, Smad 2/3 and phosphorylated Smad 2/3 (pSmad 2/3) in the jugal tissues of animals submitted to oral mucositis.