Considering the primary role of hypertension in AAAD, total RNAs were extracted from serum samples of AAAD− controls with normal blood pressure (HPT−/AAAD−), AAAD− individuals with hypertension (HPT+/AAAD−), AAAD+ patients with normal blood pressure (HPT−/AAAD+), and AAAD+ patients with hypertension (HPT+/AAAD+), respectively. The gene discussed is MRS2; the disease is Hypertension.