Of particular interest in the present study, we have detected an increase of these markers of inflammation following IH exposure, including an increase of NO and ROS production, an activation of the inflammatory pathway p65-NFκB associated with the secretion of IL-6 by endothelial cells, and an increase of in vitro transendothelial migration of monocytes. The gene discussed is NFKB1; the disease is isolated hemihyperplasia.