Foxp1-Shq1f/f;Ptenf/f mice showed accelerated oncogenesis with highly anaplastic histopathology compared to Ptenf/f mice, while Foxp1-Shq1f/f mice showed no obvious prostate cancer phenotype (Figs. 2a, b; Supplementary Fig. 2). The gene discussed is FOXP1; the disease is Familial prostate cancer.