All Foxp1-Shq1f/f;Ptenf/f mice developed intraductal carcinoma by 6 months compared to 43% of Ptenf/f mice, and 60% developed invasive carcinoma24 by 9 months of age compared to no Ptenf/f mice at 9 months and less than 30% of Ptenf/f mice by 12 months (Fig. 2b, Supplementary Fig. 2). This evidence concerns the gene FOXP1 and carcinoma.