FOXP1 and prostate neoplasm: Expression signatures of differentiation were repressed (FDR < 0.01, gene set enrichment analysis (GSEA)) in Foxp1-Shq1f/f;Ptenf/f prostate tumors, which exhibit distinct gene expression patterns from Ptenf/f tumors by unsupervised RNA-seq clustering as well as repression of Foxp factor-derived expression signatures when compared to Ptenf/f tumors (Supplementary Fig. 5).