CXCL8 and infection: According to a clinical study of Vargas et al. the decision on survival or death in septic shock develops between 40 and 60 h post infection (probably the decision is already taken somewhat earlier, between 12 and 24 h) and can be predicted from the serum pattern of the inflammation markers IL-6 and IL-8 as well as the adhesion molecules sELAM-1 and sICAM-1 [20].