IL2 and colitis: We have previously reported that the glutamine salt of the S,S -enantiomer of thecarboxylic acid derivative of PH5, PH46A has good efficacy in both DSS-colitis andthe IL10−/− model of spontaneous colitis, models with verydifferent aetiologies.[32] Furthermore, PH46A does not inhibit IL2 release from Jurkatcells (see Fig.S5).