CD274 and neoplasm: Nevertheless, Gong et al. [38] found in 64 patients with MCL differences in cytoplasmic C-MYC expression, Ki-67 proliferative index of tumor cells, and CD8 positive tumor-infiltrating lymphocytes (CD8 + TIL) among three risk groups; no significant differences existed in the expression of nuclear C-MYC, SOX11, p53, and PD-L1.