TNFSF10 and obesity due to melanocortin 4 receptor deficiency: To address this hypothesis, we evaluated the serum levels of a panel of adipokines that were selected because of their well-recognized function in low-grade inflammation and onset of metabolic disturbances, and we explored the possible associations with soluble TRAIL in a cohort of healthy postmenopausal women with different degrees of abdominal fat accumulation up to obesity.