PRRT2 and Dyskinesia: Intriguingly, in vivo light stimulation of ChR2 in AAV-infected cerebellar neurons induces dyskinesia in GluN2C-iCre;Prrt2−/− mice (Figure 5J and 5K; Supplementary information, Movie S7), indicating that a PRRT2 function within cerebellar GCs is critical for normal movement control.