Although these authors were not able to identify any mutation in this region, including the mutation described in human breast cancer (c.309C > G, [reviewed in 49]), they found two germline variants in the TWIST1 gene intron in some of the carcinomas’ samples, namely GQ167299:g.535delG and GQ167299:g.460C > T [49]. This evidence concerns the gene TWIST1 and breast carcinoma.