ADIPOQ and congestive heart failure: Healthy dogs expressed similar myocardial concentrations of HMW (10.8 ± 3.4 μg/mL) and LMW (9.2 ± 2.9 μg/mL, p = 0.46) adiponectin isoforms, whereas CHF dogs expressed significantly greater concentrations of HMW isoforms (18.8 ± 2.6 μg/mL, p < 0.001) and significantly lower concentrations of LMW isoforms (1.5 ± 0.2 μg/mL, p = 0.005) adiponectin (Figure 4 and Figure 5).